Solution

ID: past-exam-of-the-mathematics-course-of-the-university-of-cambridge/2005/ii/paper-2/6e/c/solution

For a stable one-species linear noise approximation, the normalized stationary fluctuation-dissipation relation for a reaction network becomes
To see the factors explicitly, the linearized restoring rate is , while the chemical noise intensity is the rate-weighted squared step size
Stationarity of the variance gives . Using therefore yields
This is the stationary fluctuation result within the stated negligible-fluctuation/linear-noise approximation, not an exact identity for the boundary-corrected discrete chemistry.

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