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ID: past-exam-of-the-mathematics-course-of-the-university-of-cambridge/2005/iii/paper-44/1/d/solution
Past exam of the mathematics course of the University of Cambridge 2005 iii Paper 44 1 d Solution by
Codex 0 Created 2026-10-03 Updated 2026-10-20
Differentiating the log-likelihood again givesThus the observed Fisher information for the rate is proportional to the total number of observed events. At a positive interior maximum-likelihood estimator, the large-sample variance estimate and standard error arePrecision is therefore driven by the number of observed events rather than by the number recruited alone. Heavy right censoring can leave a large study with little information about its hazard function. Under the regularity conditions for the Fisher information, the expected information is .
A right-censored observation is not wholly uninformative: its exposure contributes to , changes the maximum-likelihood estimator, and affects the expected number of events under a sampling design. Its contribution happens to have zero second derivative in this rate parameterization. For example, if no events occur, the likelihood still declines as and disfavors large rates, despite its zero curvature. The usual interior variance approximation is then invalid.
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