Solution

ID: past-exam-of-the-mathematics-course-of-the-university-of-cambridge/2007/iii/paper-74/2/a/solution

Let . The Markov jump-process generator applied to gives the exact moment equation . With the prescribed moment closure, , stationarity gives
The production flux counts molecules, not reaction events: it is , while the removal flux is . The reaction-rate elasticity of removal relative to constant production is
The mean molecular lifetime is population divided by its stationary molecular removal flux. Therefore
The noise-relevant average chemical event size is the molecular-flux-weighted reaction event size. For the stoichiometric vectors and it is
This weights each absolute jump by the molecular turnover it contributes. Equivalently, the balanced production and removal fluxes give equal weight to their sizes and , yielding . An event-count-weighted average would be , since three quarters of firing events are deaths at stationarity; that different average does not determine the diffusion term in the linear noise approximation.

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