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1Dynamics of phosphoinositide conversion in clathrin-mediated endocytic traffic by Kangmin He and othersdynamics-of-phosphoinositide-conversion-in-clathrin-mediated-endocytic-traffic-by-kangmin-he-and-others2026-10-202026-10-20
1Stretching single talin rod molecules activates vinculin binding by Armando del Rio and othersstretching-single-talin-rod-molecules-activates-vinculin-binding-by-armando-del-rio-and-others2026-10-202026-10-20
1Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment by Rowena McBeath and otherscell-shape-cytoskeletal-tension-and-rhoa-regulate-stem-cell-lineage-commitment-by-rowena-mcbeath-and-others2026-10-202026-10-20
1Role of YAP/TAZ in mechanotransduction by Sirio Dupont and othersrole-of-yap-taz-in-mechanotransduction-by-sirio-dupont-and-others2026-10-202026-10-20
1Matrix crosslinking forces tumor progression by enhancing integrin signaling by Kandice R. Levental and othersmatrix-crosslinking-forces-tumor-progression-by-enhancing-integrin-signaling-by-kandice-r-levental-and-others2026-10-202026-10-20
1Sar1p N-terminal helix initiates membrane curvature and completes the fission of a COPII vesicle by Marcus C. S. Lee and otherssar1p-n-terminal-helix-initiates-membrane-curvature-and-completes-the-fission-of-a-copii-vesicle-by-marcus-c-s-lee-and-others2026-10-202026-10-20
1Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape by Joshua Hutchings and otherssubtomogram-averaging-of-copii-assemblies-reveals-how-coat-organization-dictates-membrane-shape-by-joshua-hutchings-and-others2026-10-202026-10-20
1Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles by Elizabeth A. Miller and othersmultiple-cargo-binding-sites-on-the-copii-subunit-sec24p-ensure-capture-of-diverse-membrane-proteins-into-transport-vesicles-by-elizabeth-a-miller-and-others2026-10-202026-10-20
1TANGO1 facilitates cargo loading at endoplasmic reticulum exit sites by Kota Saito and otherstango1-facilitates-cargo-loading-at-endoplasmic-reticulum-exit-sites-by-kota-saito-and-others2026-10-202026-10-20
1Isolation of the coenzyme of the galactose phosphate-glucose phosphate transformation by R. Caputto and othersisolation-of-the-coenzyme-of-the-galactose-phosphate-glucose-phosphate-transformation-by-r-caputto-and-others2026-10-202026-10-20
1X-ray structure of a bacterial oligosaccharyltransferase by Christian Lizak and othersx-ray-structure-of-a-bacterial-oligosaccharyltransferase-by-christian-lizak-and-others2026-10-202026-10-20
1Schizosaccharomyces pombe UDP-galactose transporter: identification of its functional form through cDNA cloning and expression in mammalian cells by Hiroaki Segawa and othersschizosaccharomyces-pombe-udp-galactose-transporter-identification-of-its-functional-form-through-cdna-cloning-and-expression-in-mammalian-cells-by-hiroaki-segawa-and-others2026-10-202026-10-20
1Crystallographic snapshot of cellulose synthesis and membrane translocation by Jacob L. W. Morgan and otherscrystallographic-snapshot-of-cellulose-synthesis-and-membrane-translocation-by-jacob-l-w-morgan-and-others2026-10-202026-10-20
1Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses by Rosario Rizzuto and othersclose-contacts-with-the-endoplasmic-reticulum-as-determinants-of-mitochondrial-ca2-plus-responses-by-rosario-rizzuto-and-others2026-10-202026-10-20
1ER-mitochondria tethering by PDZD8 regulates Ca2+ dynamics in mammalian neurons by Yusuke Hirabayashi and otherser-mitochondria-tethering-by-pdzd8-regulates-ca2-plus-dynamics-in-mammalian-neurons-by-yusuke-hirabayashi-and-others2026-10-202026-10-20
1An ER-mitochondria tethering complex revealed by a synthetic biology screen by Benoît Kornmann and othersan-er-mitochondria-tethering-complex-revealed-by-a-synthetic-biology-screen-by-benoit-kornmann-and-others2026-10-202026-10-20
1A phospholipid transfer function of ER-mitochondria encounter structure revealed in vitro by Rieko Kojima and othersa-phospholipid-transfer-function-of-er-mitochondria-encounter-structure-revealed-in-vitro-by-rieko-kojima-and-others2026-10-202026-10-20
1ER tubules mark sites of mitochondrial division by Jonathan R. Friedman and otherser-tubules-mark-sites-of-mitochondrial-division-by-jonathan-r-friedman-and-others2026-10-202026-10-20
1Production of very long chain polyunsaturated omega-3 and omega-6 fatty acids in plants by Baoxiu Qi and othersproduction-of-very-long-chain-polyunsaturated-omega-3-and-omega-6-fatty-acids-in-plants-by-baoxiu-qi-and-others2026-10-202026-10-20
1Biosynthesis of very-long-chain polyunsaturated fatty acids in transgenic oilseeds: constraints on their accumulation by Amine Abbadi and othersbiosynthesis-of-very-long-chain-polyunsaturated-fatty-acids-in-transgenic-oilseeds-constraints-on-their-accumulation-by-amine-abbadi-and-others2026-10-202026-10-20

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Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Video 1.
Intro to OurBigBook
. Source.
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
    Video 2.
    OurBigBook Web topics demo
    . Source.
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact
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