Brain simulation

www.nature.com/articles/d41586-019-02209-z The four biggest challenges in brain simulation (2019)

Table of contents
- Brain-in-the-loop Brain simulation
- Animal-in-the-loop Brain simulation

Brain-in-the-loop

Ciro Santilli invented this term, derived from "hardware in the loop" to refer to simulations in which both the brain and the body and physical world of organism models are modelled.

E.g. just imagine running:

NeuroMechFly
a Drosophila connectome simulation

Animal-in-the-loop

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Ciro Santilli invented this term, it refers to mechanisms in which you put an animal in a virtual world that the animal can control, and where you can measure the animal's outputs.