An enzyme that hydrolyzes the beta-lactam ring of susceptible antibiotics. Substrate specificity and catalytic mechanisms vary among classes and variants.
A TEM-family beta-lactamase variant whose structure and substrate specificity differ from TEM-1. Controlled comparisons distinguish access remodeling, catalytic behavior and altered expression.[ref]
A reference TEM-family class A beta-lactamase against which altered-spectrum variants can be compared.
Articles by others on the same topic
There are currently no matching articles.