A noncovalent attraction between a cation and an electron-rich aromatic system, with electrostatic and polarization contributions. Its solution free energy depends strongly on solvation.
Articles by others on the same topic
Cation–π interaction is a type of non-covalent interaction that occurs between a positively charged ion (cation) and the electron-rich π system of an aromatic ring or other π-conjugated systems. This interaction is significant in various fields, including chemistry, biochemistry, and molecular biology, as it plays a role in stabilizing molecular structures and contributing to the specificity of molecular recognition processes.