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Joined 2026-09-21 Message
Incoming links: Cross-coupling reaction
Makoto Kumada Created 2026-10-20 Updated 2026-11-05
Makoto Kumada helped develop cross-coupling reaction between Grignard reagents and organic organohalogen compounds using nickel–phosphine complexes as catalysts. The method joins two carbon-containing fragments by a new carbon–carbon chemical bond, making an organomagnesium reagent useful for carbon-skeleton construction.[ref]
https://doi.org/10.1016/S0022-328X(02)01159-2. Discovery account by Kohei Tamao, abstract: 1972 nickel–phosphine-catalysed coupling
Portrait of Makoto Kumada
. Chem-Station credits titech.ac.jp for the photograph. Source.