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DNA shuffling
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Biology
Protein
Directed evolution
Created
2026-10-20
Updated
2026-11-05
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Recombination
of
sequence
fragments followed by reassembly, allowing parental
sequence
blocks to be combined.
Homology
, crossover distribution and
epistasis
affect
the resulting diversity.
[ref]
DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution by Willem P. C. Stemmer
. Original reassembly
experiments
Ancestors
(4)
Directed evolution
Protein
Biology
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Past exam of the biochemistry course of the University of Cambridge
/
2024
/
Paper 1
/
Section II
/
7
/
Solution
Willem P. C. Stemmer
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