Study of gene functions and interactions using perturbations and genome-scale measurements. Expression correlation and causal requirement are different forms of evidence.
A perturbation restricted to a chosen tissue or lineage. Driver specificity and indirect effects through neighbouring tissues must be validated.
A perturbation initiated or terminated at a chosen time to separate earlier specification from later growth or maintenance. Recombination and protein-depletion delays require measurement.
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Functional genomics is a branch of molecular biology that focuses on understanding the relationship between an organism's genome (the complete set of its genetic material) and its biological function. This field aims to elucidate how genes and their products (such as proteins) interact and contribute to cellular processes, organism development, and overall organismal phenotype.