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E. Margaret Burbidge helped connect observed stellar elemental abundances with stellar nucleosynthesis in the 1957 synthesis written with G. R. Burbidge, William Alfred Fowler and Fred Hoyle. Their account combined stellar burning stages and nuclear reactions into an explanation of how stars build many chemical elements.^[ref]

The abundance pattern acts as a physical constraint: a proposed nuclear reaction sequence must account for relative yields, rather than merely produce an element in principle.

G. R. Burbidge co-developed the 1957 account of stellar nucleosynthesis with E. Margaret Burbidge, William Alfred Fowler and Fred Hoyle. The work distinguished slow neutron-capture processes from rapid neutron-capture processes by comparing neutron capture and radioactive-decay timescales.^[ref]

That ordering matters because a nucleus can either capture another neutron or decay first, producing different paths through the nuclides and different final abundance patterns.