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Joined 2026-09-21 Message
Incoming links: Gene therapy
Gene therapy 2026-11-05
Gene therapy uses delivery, replacement or modification of genetic material to change cellular function for a therapeutic purpose. It includes gene addition as well as some forms of genome editing; changing the inherited germline is not required. The delivered sequence, delivery system and target cell type are distinct components of the intervention. [ref]
An experimental example introduced a long-wavelength opsin into adult dichromatic squirrel monkeys. Behavioural colour-discrimination measurements changed after treatment, linking genetic delivery to a functional sensory outcome in that model. This was an adult primate experiment, not a demonstration that the same intervention works for every human visual disorder. [ref]
Gene therapy for red-green colour blindness in adult primates by Katherine Mancuso and others. 2009, adult squirrel-monkey treatment and colour-discrimination testing
Katherine Mancuso Created 2026-10-20 Updated 2026-11-05
A researcher who coauthored an experiment adding an opsin to the retina of adult Primates through gene therapy. Subsequent behavioral testing showed new colour vision discrimination, connecting a molecular intervention to a measured perceptual ability.[ref]
Gene therapy for red-green colour blindness in adult primates by Katherine Mancuso and others. 2009, abstract and behavioral results