The Hochschild cochains are , with coboundary
The Hochschild cohomology groups are
A -linear derivation from a -algebra to an --bimodule is a map satisfying
For , the formula defines an inner derivation .
The degree-one Hochschild cocycles are exactly the maps that are a derivation into a bimodule, while degree-one coboundaries are exactly the inner derivations. Therefore
Let be multiplication and , with the outer -bimodule structure. Then
is a derivation and composition with gives a natural isomorphism
The inverse sends to
The condition makes this map left as well as right -linear. Every element of is a sum of terms , which proves uniqueness.
Under the universal isomorphism, the inner derivation corresponds to
Thus inner derivations correspond exactly to bimodule maps on that extend across the inclusion .

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