A -linear derivation from a -algebra to an --bimodule is a map satisfying
For an associative algebra over a field , a derivation is a -linear map satisfying . It is the case of a derivation into a bimodule; the order of factors matters when is noncommutative. Substituting gives . Such maps form a Lie algebra under the commutator .
More generally, for a commutative ring , a derivation from a commutative -algebra into a -module is an -linear map with for and . The second term has this order because the algebra is commutative. Derivations of smooth functions are vector fields provide a geometric example.
Every real-linear derivation of an algebra on a smooth manifold has the form for a unique smooth vector field . The product rule makes local: multiplying a function that vanishes near a point by a smooth cutoff function supported there gives zero derivative at that point. Locally write , where . Applying at gives ; the smooth coefficients define the claimed vector field. No continuity hypothesis is needed. In dimension zero all such derivations vanish.
For , the formula defines an inner derivation .
The degree-one Hochschild cocycles are exactly the maps that are a derivation into a bimodule, while degree-one coboundaries are exactly the inner derivations. Therefore
Let be multiplication and , with the outer -bimodule structure. Then
is a derivation and composition with gives a natural isomorphism
The inverse sends to
The condition makes this map left as well as right -linear. Every element of is a sum of terms , which proves uniqueness.
Under the universal isomorphism, the inner derivation corresponds to
Thus inner derivations correspond exactly to bimodule maps on that extend across the inclusion .

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