A stem cell contributing sustained differentiated descendants to the intestinal lining. Marker expression is suggestive; long-term lineage tracing tests renewal and lineage output.
A functional description for a cell that can restore intestinal stem-cell output after damage. It does not by itself establish a permanently distinct, uniquely marked quiescent lineage.
A cell at the crypt base, including actively cycling Lgr5-expressing stem cells interspersed with supporting cells in the mouse small intestine.

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  1. Stem cell
  2. Biological cell
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