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For central $t_1,\dots ,t_n$, define the Koszul complex on central ring elements using formal exterior symbols:with zero terms outside $0\le k\le n$ and differentialThe terms are free bimodules with the formal symbols commuting with coefficients. Centrality makes $d$ a bimodule map, and the terms in $d^2$ cancel in pairs because the $t_i$ commute. This defines the Koszul complex over a possibly noncommutative ring without using an undefined exterior algebra of arbitrary one-sided modules. In particular $K(\mathbf{t}){\otimes }_{R}M$ is a well-defined chain complex of left modules.

A regular sequence on a module means that multiplication by $t_i$ is injective on $M/(t_1,\dots ,t_{i-1})M$ for each $i$, usually with the additional convention that the final quotient is nonzero. The homology vanishing below uses only the injectivity conditions. For one element, the chain complex is $M\stackrel{t_1}{\to }M$, with zero first homology and zeroth homology $M/t_{1}M$.

For the induction let $C=K(t_1,\dots ,t_{n-1}){\otimes }_{R}M$. Adjoining the last generator identifies the new Koszul complex with the mapping cone of multiplication by $t_n$ on $C$. In the convention $\mathrm{Cone}(t_n{)}_k=C_k\oplus C_{k-1}$ its differential is $(a,b)\mapsto (da+t_{n}b,-db)$; the identification is $a+e_n\wedge b$. The long exact sequence in homology of this mapping cone givesThe induction hypothesis is $H_k(C)=0$ for $k>0$ and $H_0(C)=N=M/(t_1,\dots ,t_{n-1})M$. Regularity makes $t_n:N\to N$ injective. Hence the new positive homology is zero and its zeroth homology is $N/t_{n}N$. The augmentation to this quotient induces these homology isomorphisms, giving the quasi-isomorphismwhere the right side is placed in degree zero. The results used are the long exact sequence in homology of a degreewise short exact sequence of complexes and its mapping cone form, together with the stated induction; no unmentioned acyclicity criterion is needed.

For $R=\mathbb{Z}[X]$, $(p,X)$ is a regular sequence: $p$ is a non-zero-divisor in $R$, and multiplication by $X$ is injective in $(\mathbb{Z}/p\mathbb{Z})[X]$, even when $p$ is composite. The Koszul resolution of $R/(p,X)$ isWith $N=\mathbb{Z}/q\mathbb{Z}$ and $X$ acting as zero, applying the Hom functor gives the cochain complexThus, more generally, the Ext groups between polynomial-ring residue modules areand vanish in all degrees above two. For the equal-modulus case,These are $R$-modules through $X=0$ and reduction modulo $p$. If the multiplicative self-Ext functor is desired, the Koszul self-Ext algebra is the exterior algebra on two degree-one generators over $\mathbb{Z}/p\mathbb{Z}$. The two contractions on the Koszul resolution lift these classes, square to zero and anticommute, so this description also holds for composite $p$ and characteristic two. For coprime $p,q$, multiplication by $p$ is invertible on $N$, so both its kernel and cokernel vanish:

For central elements, each multiplication map on the preceding quotient must be injective; a usual convention also requires the final quotient to be nonzero. The augmented Koszul complex on central ring elements tensored with $M$ is then a quasi-isomorphism to the final quotient in degree zero.