Covariate-dependent missing completely at random Created 2026-10-14 Updated 2026-11-05
Missingness depends only on fully observed covariates , not on the response after conditioning on them. A responder-only marginal estimate may still be biased when response rates and outcome probabilities both vary across covariate strata. MAR standardization over a fully observed covariate weights within-stratum respondent estimates using covariate frequencies from the whole target cohort.
Assume that, conditional on the recorded embarrassment category, answering the item is independent of virginity status. Also assume that this category is assessed comparably for both groups and that both response strata have positive observation probabilities. This is covariate-dependent missing completely at random for the item response with embarrassment as the fully observed covariate; it supports MAR standardization over a fully observed covariate.
Use the responder probabilities and within strata, but the stratum sizes in the full group of responders plus item nonresponders: and . This gives
Equivalently, the estimated missing positive counts are and , adding 22 to the 68 observed positives. The marginal estimate changes because the full group contains a larger proportion judged embarrassed. Merely copying the unstratified responder percentage would ignore that difference. The conditional independence assumption cannot be verified using the missing item responses.
Apply MAR standardization over a fully observed covariate. All first-year statuses are known, so the estimated probabilities of no use and use in year one are and . Within those categories, missing at random lets the observed second-year probabilities represent the corresponding dropout outcomes as well. They are estimated by and .
The law of total probability then gives
Equivalently, impute expected drug-use counts and for the two dropout groups, add these to the 25 observed second-year users, and divide by 102. This uses both the complete records and the fully observed first-year information.