A mechanosensitive ion channel changes gating in response to mechanical conditions transmitted through the membrane or associated structures. A changed calcium signal alone does not identify which channel or mechanical coupling was responsible.
A large-conductance bacterial mechanosensitive channel serving as an emergency release pathway under high membrane tension.
A bacterial mechanosensitive channel that can release solutes during sudden osmotic downshock.

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  1. Ion channel
  2. Cell membrane
  3. Biological cell
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