Norepinephrine, also called noradrenaline, is a catecholamine neurotransmitter used in central and peripheral signaling. Its effects on attention, arousal or a peripheral organ depend on the target receptor and the local cellular machinery.
The same chemical signal can thus have different physiological consequences in different tissues. Measuring a whole-body concentration and recording a local synaptic response answer different questions; neither alone identifies a universal scalar level of arousal.

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