Dulac theorem states the following. Let be a simply connected region for the planar system , and suppose there is a continuously differentiable function for which
has one strict sign throughout . Then there is no periodic orbit contained in .
To prove it, suppose a periodic orbit existed and let be its interior. Simple connectedness ensures . By the planar divergence theorem,
The vector field is tangent to its trajectory , so its scalar product with the outward normal vanishes. The right-hand side is therefore zero. The left-hand side cannot be zero because its integrand has one strict sign, a contradiction.
The Poincare-Bendixson theorem states that if a forward trajectory of a smooth planar system remains in a compact set and its nonempty omega-limit set contains no equilibrium point, then that omega-limit set is a periodic orbit.
At an equilibrium point of a dynamical system, the second equation gives
The choice is impossible because then . Hence , and substitution into the first equation gives
Thus the unique fixed point is
Choose
which satisfies . Let
We check the direction of the vector field on its four edges.
On ,
On ,
On , where ,
Finally, throughout the system,
On the sloping edge , the bound implies , and hence . Every boundary edge therefore points inward. Violations of the corresponding four inequalities are driven toward the boundary in the same order, so positive trajectories enter this compact trapping region and then remain there. This is the Brusselator trapping region.
The Jacobian matrix at the unique fixed point is
Its determinant and trace are
When , the trace is positive, so linear stability of a planar equilibrium shows that the fixed point is a repeller. It lies in the interior of .
Choose a trajectory in other than the equilibrium. Compactness of gives a nonempty compact omega-limit set, and the repelling equilibrium cannot belong to that set. Since there are no other equilibria, the Poincare-Bendixson theorem gives a periodic orbit. Hence
This is the Brusselator periodic-orbit criterion.

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