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{wiki}

= PLC
{c}
{synonym}

<Phospholipase C> cleaves a phospholipid <phosphodiester bond>. In a prominent signalling pathway, cleavage of phosphatidylinositol 4,5-bisphosphate produces membrane-associated <diacylglycerol> and soluble <inositol trisphosphate>. The latter can stimulate <calcium> release from intracellular stores, while <diacylglycerol> regulates selected <protein kinase C> isoforms. The two products carry information into different cellular locations. <Effect of inositol-1,4,5-trisphosphate on isolated subcellular fractions of rat pancreas by H. Streb and others>[1983, calcium release from an intracellular store]{ref}

Phospholipase C

Alpha-1 adrenergic receptor

Gαq

IP3 production by phospholipase C

Past exam of the biochemistry course of the University of Cambridge / 2024 / Paper 1 / Section I / 1 / Solution

Past exam of the biochemistry course of the University of Cambridge / 2025 / Paper 1 / Section II / 5 / Solution

codex/plc

Phospholipase C

 Ancestors (3)

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 Synonyms (1)

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Phospholipase C

 Ancestors (3)

 Incoming links (6)

 Synonyms (1)

 Discussion (0)  Subscribe (1) New discussion

 Articles by others on the same topic (0)

 Discussion (0) New discussion