Regulation involving production, accumulation and detection of extracellular signals. Signal concentration depends on transport and environment as well as population density.
The Pseudomonas aeruginosa quinolone-signaling network involving HHQ/PQS, PqsR and the pqs biosynthetic locus.
The Pseudomonas aeruginosa RhlI/RhlR system, whose regulation of virulence-factor production is linked to PqsE and the broader signaling network.
The Pseudomonas aeruginosa LasI/LasR acyl-homoserine-lactone signaling system, often upstream of additional quorum-sensing circuits in laboratory strains.
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Quorum sensing is a cellular communication process used by bacteria and some other microorganisms to coordinate their behavior based on population density. It enables them to detect and respond to the presence of other cells in their environment through the release and detection of signaling molecules called autoinducers. When the concentration of these signaling molecules reaches a certain threshold, it indicates that a sufficient number of bacterial cells are present. This allows bacteria to trigger collective behaviors that are more effective when executed by a larger group.