SHATTERPROOF1 is an Arabidopsis thaliana gene encoding a MADS-box transcription factor involved in fruit dehiscence. The gene's product helps specify the dehiscence zone, the specialized region along which a mature fruit opens.[ref]
Its relationship with SHATTERPROOF2 illustrates compensation between related genes. In the reported experiment, the single mutant did not show the novel opening defect seen when both functions were disrupted. Consequently, a normal-looking single mutant does not establish that SHATTERPROOF1 has no developmental role; the appropriate comparison includes the double mutant.[ref]

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