A SNARE complex is an assembly of complementary SNARE proteins, commonly forming a four-helix bundle. A trans complex bridges opposing membranes and can promote membrane fusion; after fusion, its components occupy the same membrane in a cis complex. ATP-dependent disassembly permits component reuse. This distinction explains why detecting a complex alone does not determine whether it is a fusion intermediate or a product remaining after fusion. [ref]
A trans-SNARE complex links SNARE proteins anchored in different lipid bilayers. Its formation can bring membranes together before complete membrane fusion.

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  1. SNARE protein
  2. Membrane fusion
  3. Cell membrane
  4. Biological cell
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