Daniel Mateju Created 2026-10-20 Updated 2026-11-05
A stress-associated RNA–protein assembly whose formation and composition depend on context. RNA enrichment does not establish obligatory translational silence.
G3BP2 Created 2026-10-20 Updated 2026-11-05
G3BP2 is an RNA-binding protein involved in the organization of stress granules. Together with related components, it helps couple RNA-protein interactions to formation of a condensed cytoplasmic assembly. The granule state depends on concentration, binding partners and stress context. Presence of G3BP2 in a granule supports participation, while testing a requirement for assembly needs depletion or a defined functional perturbation. [ref]
Nancy Kedersha Created 2026-10-20 Updated 2026-11-05
A stress-associated RNA–protein assembly whose formation and composition depend on context. RNA enrichment does not establish obligatory translational silence.