Surface plasmon resonance can monitor binding near an optical sensor surface in real time through refractive-index changes. Concentration-dependent association and dissociation can constrain kinetics, subject to controls for nonspecific binding, transport limitation and multivalency.
A resonant collective electronic response confined to a finite conducting nanostructure. Its near field depends on geometry, environment and loss.
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Surface Plasmon Resonance (SPR) is an optical technique used to measure the binding interactions between biomolecules in real time and without the need for labeling. It exploits the unique properties of surface plasmons, which are coherent oscillations of free electrons at the surface of a conductor, typically at the interface between a metal (usually gold or silver) and a dielectric medium (often water or air).