Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery by Mei-Chu Lo and others 2026-11-05
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By Mei-Chu Lo and colleagues. Analytical Biochemistry332(1),153–159(1September2004). DOI doi.org/10.1016/j.ab.2004.04.031
Abstract: environmentally sensitive dye readout, ligand/control thermal shift, commercial temperature/fluorescence instrument, comparison with isothermal titration calorimetry and activity assays.
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