CHRNA5 refers to the gene that encodes the alpha-5 subunit of the nicotinic acetylcholine receptor (nAChR). This receptor is a type of ligand-gated ion channel that plays a critical role in neurotransmission in the nervous system by mediating the effects of the neurotransmitter acetylcholine. The CHRNA5 gene is located on chromosome 15 in humans and is part of a cluster of genes that encode components of nicotinic receptors.
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