 Computer Atlas of Surface Topography of Proteins

The Computer Atlas of Surface Topography of Proteins (CASTp) is a computational tool and database designed to analyze the surface topology of proteins. It provides detailed information about the surface characteristics of protein structures, including information about cavities, channels, and pockets on protein surfaces. CASTp uses algorithms to identify and characterize these topographical features based on the three-dimensional coordinates of protein structures, typically derived from X-ray crystallography, NMR spectroscopy, or computational modeling.