 Critical closing pressure

Critical closing pressure (CCP) refers to the minimum pressure required to prevent the collapse of a blood vessel, particularly a vein, during diastole (the phase of the heartbeat when the heart relaxes and fills with blood). This concept is especially relevant in the context of venous circulation, where maintaining proper blood flow and preventing stasis (the slowing or stopping of blood flow) are crucial for ensuring adequate circulation and preventing conditions like venous thromboembolism.