E. Coli K-12 MG1655 gene of unknown function by Ciro Santilli 34 Updated 2024-11-19 Created 1970-01-01
UniProt for example describes YaaX as "Uncharacterized protein YaaX".
As function is discovered, they then change it to a better name, e.g. to names such as the E. Coli K-12 MG1655 transcription unit thrLABC proteins all of which have a clear name due to threonine.
There are many other
y???
as of 2021! Though they do tend to be smaller molecules.