McDonald–Kreitman test
ID: mcdonald-kreitman-test
The McDonald–Kreitman test is a statistical method used in evolutionary biology to assess the role of natural selection versus neutral evolution in shaping genetic variation within a population. Developed by biologists Brian McDonald and David Kreitman in the 1990s, the test compares the ratio of synonymous to nonsynonymous substitutions in a particular gene or set of genes.
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