The term "metallome" refers to the comprehensive study of metal ions in biological systems, similar to how the genome refers to the complete set of genes in an organism and the proteome refers to the entire set of proteins. The metallome focuses on understanding the role of various metal ions—such as zinc, copper, iron, and manganese—in biological processes, including their involvement in enzyme catalysis, signaling pathways, and structural functions in proteins and nucleic acids.
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