Ryanodine receptor 1 (RyR1) is a calcium release channel located in the sarcoplasmic reticulum (SR) of skeletal muscle cells. It plays a critical role in the process of muscle contraction by releasing calcium ions (Ca²⁺) into the cytoplasm when the muscle is stimulated. This released calcium then binds to proteins such as troponin, leading to muscle contraction through the sliding filament mechanism.
New to topics? Read the docs here!