- www.cell.com/cell/fulltext/S0092-8674(15)00568-1 2015. Using Genome-scale Models to Predict Biological Capabilities. Edward J. O'Brien, Jonathan M. Monk, Bernhard O. Palsson.
- www.quora.com/What-are-some-good-books-on-Escherichia-Coli-E-Coli
Size: 1-2 micrometers long and about 0.25 micrometer in diameter, so:
2 * 0.5 * 0.5 * 10e-18
and thus 0.5 micrometer square.Reference strain: E. Coli K-12 MG1655.
Genome:
- 4k genes
- 5 Mbps
- www.ncbi.nlm.nih.gov/genome/167
wget ftp://ftp.ncbi.nlm.nih.gov/genomes/all/GCF/000/005/845/GCF_000005845.2_ASM584v2/GCF_000005845.2_ASM584v2_genomic.fna.gz
wget -O NC_000913.3.fasta 'https://www.ncbi.nlm.nih.gov/search/api/sequence/NC_000913.3/?report=fasta'
Synthesis project: www.sciencemag.org/news/2016/08/biologists-are-close-reinventing-genetic-code-life
Omics modeling: www.ncbi.nlm.nih.gov/pmc/articles/PMC5611438/ Tools for Genomic and Transcriptomic Analysis of Microbes at Single-Cell Level Zixi Chen, Lei Chen, Weiwen Zhang.
The mantra of the computer simulation engineer.
Boooooring.
These are the rules which specify what different concurrent read/write memory accesses from different threads/processes can or cannot see.
Notable such set of rules include:
- C++ memory model. These are also reflected on the semantics of memory of the corresponding instruction set architecture
- SQL transaction isolation level
uknqt.ukri.org/wp-content/uploads/2021/10/UKNQTP-Strategic-Intent-2020.pdf page 24 mentions UKNQTP investment and gives an overview of some layers.
Like isomorphism, but does not have to be one-to-one: multiple different inputs can have the same output.
This brings us to the key intuition about group homomorphisms: they are a way to split out a larger group into smaller groups that retains a subset of the original structure.
As shown by the fundamental theorem on homomorphisms, each group homomorphism is fully characterized by a normal subgroup of the domain.
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