Points in the direction in which a wind spinner spins fastest.
Integrates its RNA genome into the host genome.
- first RNA to DNA with reverse transcriptase
- then injects DNA into host genome with integrase
Sounds complicated! The advantage is likely as in HIV: once inside the cell, it can remain hidden far away from the cell surface, but still infections.
They were basically a Microsoft of their century. A little less monopolistic perhaps as countries believed they should own they natural resources, unlike their data.
TODO human presumably?
I don't think it has any advantage over KEGG however, besides historical interest? Maybe slightly more manual layout and so more beautiful?
James Somers (rightly) likes to point to it as a "biology is awesome" thing.
The one true game engine!
The fundamental insight of Git design is: a SHA represents not only current state, but also the full history due to the Merkle tree implementation, see notably:
This makes it so that you will always notice if you are overwriting history on the remote, even if you are developing from two separate local computers (or more commonly, two people in two different local computers) and therefore will never lose any work accidentally.
It is very hard to achieve that without the Merkle tree.
Consider for example the most naive approach possible of marking versions with consecutive numbers:
- Local 1:
- 0: root commit
- 1: commit 1
- 2: commit 2 by local 1
- Local 2:
- 0: root commit
- 1: commit 1
- 2: commit 2 by local 2
- 3: commit 3 by local 2
- Remote
- 0: root commit
- 1: commit 1
If Local 1 were to push to Remote first, how could Local 2 notice that when it tries to push itself? The navie method of just checking: "does Remote have commit "2"" does not work, because Local 2 has a different version of commit 2 than local 1.
The 1997 Wayback Machine archives are just priceless: web.archive.org/web/19971210065425/http://backrub.stanford.edu/backrub.html. I'm so glad that website exists and started so early. It is just another university research project demo website like any other. Priceless.
Craig Silverstein was the first employee hired, in 1998: www.newyorker.com/magazine/2018/12/10/the-friendship-that-made-google-huge
In August 1998 they had an their first investment of $100,000 from Andy Bechtolsheim, Sun Microsystems co-founder. Some sources say September 1998. This was an event of legend, the dude dropped by, tested the website for a few minutes, said I like it, and dropped a 100$ check with no paperwork. Google wasn't even incorporated, they had to incorporate to cash the check. They were apparently introduced by one of the teachers, TODO which. Some sources say he had to rush off to another meeting afterwards:
Tried to sell it for 1 million in early 1999... OMG the way the world is. It would be good to learn more about that story, and when they noticed it was fuckup.
One of Google's most interesting stories is how their startup garage owner became an important figure inside Google, and how Sergei married her sister. These were the best garage tenants ever!
Bibliography:
- Video "Anne Wojcicki interview by Talks at Google (2018)" has a few mentions, e.g. youtu.be/pDoALM0q1LA?t=173
- www.theverge.com/2019/12/4/20994361/google-alphabet-larry-page-sergey-brin-sundar-pichai-co-founders-ceo-timeline The rise, disappearance, and retirement of Google co-founders Larry Page and Sergey Brin. Good timeline!
Street View's go into the past mode is the dream of every archaeologist. Ciro can only dream of a magic street view that allows going back to earlier centuries and beyond... isn't it amazing to think that people in the future will have that ability to time travel back to around the year 2006? Ciro wonders how long Google will be able to keep storing data like that.
Thanks, CIA.
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