MacKenzie Bezos's charity instrument.
www.irishtimes.com/life-and-style/people/mackenzie-scott-how-the-former-mrs-bezos-became-a-philanthropist-like-no-other-1.4850049 MacKenzie Scott: How the former Mrs Bezos became a philanthropist like no other (2020) has some good mentions:
But as Scott's fame for giving away money has grown, so too has the deluge of appeals for gifts from strangers and old friends alike. That clamour may have driven Scott's already discreet operation further underground, with recent philanthropic announcements akin to sudden lightning bolts for unsuspecting recipients.
The name of the organization is a reference to the old man lost his horse.
Published as "Fine Structure of the Hydrogen Atom by a Microwave Method" by Willis Lamb and Robert Retherford (1947) on Physical Review. This one actually has open accesses as of 2021, miracle! journals.aps.org/pr/pdf/10.1103/PhysRev.72.241
Microwave technology was developed in World War II for radar, notably at the MIT Radiation Laboratory. Before that, people were using much higher frequencies such as the visible spectrum. But to detect small energy differences, you need to look into longer wavelengths.
This experiment was fundamental to the development of quantum electrodynamics. As mentioned at Genius: Richard Feynman and Modern Physics by James Gleick (1994) chapter "Shrinking the infinities", before the experiment, people already knew that trying to add electromagnetism to the Dirac equation led to infinities using previous methods, and something needed to change urgently. However for the first time now the theorists had one precise number to try and hack their formulas to reach, not just a philosophical debate about infinities, and this led to major breakthroughs. The same book also describes the experiment briefly as:
Willis Lamb had just shined a beam of microwaves onto a hot wisp of hydrogen blowing from an oven.
It is two pages and a half long.
They were at Columbia University in the Columbia Radiation Laboratory. Robert was Willis' graduate student.
Previous less experiments had already hinted at this effect, but they were too imprecise to be sure.
21 cm is very long and very low energy, because he energy split is very small!
Compare it e.g. with the hydrogen 1-2 spectral line which is 121.6 nm!
Has some good mentions, but often leaves you wanting more details of how certain things happened, especially the early days stuff.
Does however paint a good picture of several notable employees, and non-search projects from the early 2000's including:
- the cook dude
- porn cookie guy
- the unusual IPO process
Paints a very positive picture of the founders. It is likely true. They gave shares generously to early employees. Tried to allow the more general public to buy from IPO, by using a bidding scheme, rather than focusing on the big bankers as was usual.
The introduction mentions that Google is very interested in molecular biology and mining genetics data, much like Ciro Santilli! Can't find external references however...
Two of the most compelling areas that Google and its founders are quietly working on are the promising fields of molecular biology and genetics. Millions of genes in combination with massive amounts of biological and scientific data are an excellent match for the Google search engine, the tremendous database the company has in place, and its immense computing power. Already, Google has downloaded a map of the human genome and is working closely with biologist Dr. Craig Venter and other leaders in genetics on scientific projects that may lead to important breakthroughs in science, medicine, and health. In other words, we may be heading toward a time when people can google their own genes.
The book gives good highlight as to why Google became big: search was just an incredibly computationally intensive task. From very early days, Largey were already making up their own somewhat custom compute systems from very early days, which naturally led into Google custom hardware later on. Google just managed to pull ahead on the reinvest revenue into hardware loop, and no one ever caught them back. This feels more the case than e.g. with Amazon, which notoriously had to buy off dozens of competitors to clear the way.
Equation "Hydrogen spectral series mnemonic" gives for example from principal quantum number 1 to 2 a difference:which with Planck-Einstein relation gives about 121.6 nm ( Hz), which is a reasonable match with the value of 121.567... from the NIST Atomic Spectra Database.
Contained in bytes 0x40 to 0x7F.
The first section is always magic: www.sco.com/developers/gabi/2003-12-17/ch4.sheader.html says:
If the number of sections is greater than or equal to SHN_LORESERVE (0xff00), e_shnum has the value SHN_UNDEF (0) and the actual number of section header table entries is contained in the sh_size field of the section header at index 0 (otherwise, the sh_size member of the initial entry contains 0).
There are also other magic sections detailed in
Figure 4-7: Special Section Indexes
.Section type:
sh_type == SHT_STRTAB
.Common name: "section header string table".
The section name
.shstrtab
is reserved. The standard says:This section holds section names.
This section gets pointed to by the
e_shstrnd
field of the ELF header itself.String indexes of this section are are pointed to by the
sh_name
field of section headers, which denote strings.This section does not have outputs:
SHF_ALLOC
marked, so it will not appear on the executing program.readelf -x .shstrtab hello_world.o
Hex dump of section '.shstrtab':
0x00000000 002e6461 7461002e 74657874 002e7368 ..data..text..sh
0x00000010 73747274 6162002e 73796d74 6162002e strtab..symtab..
0x00000020 73747274 6162002e 72656c61 2e746578 strtab..rela.tex
0x00000030 7400 t.
The data in this section has a fixed format: www.sco.com/developers/gabi/2003-12-17/ch4.strtab.html
If we look at the names of other sections, we see that they all contain numbers, e.g. the
.text
section is number 7
.Then each string ends when the first NUL character is found, e.g. character
12
is \0
just after .text\0
.ELF is specified by the LSB:
The LSB basically links to other standards with minor extensions, in particular:
- Generic (both by SCO):
- System V ABI 4.1 (1997) www.sco.com/developers/devspecs/gabi41.pdf, no 64 bit, although a magic number is reserved for it. Same for core files. This is the first document you should look at when searching for information.
- System V ABI Update DRAFT 17 (2003) www.sco.com/developers/gabi/2003-12-17/contents.html, adds 64 bit. Only updates chapters 4 and 5 of the previous document: the others remain valid and are still referenced.
- Architecture specific (by the processor vendor):
A handy summary can be found at:
man elf
Clear experiment diagram which explains that the droplet mass determined with Stoke's law:
American Scientific, LLC sells a ready made educational kit for this: www.youtube.com/watch?v=EV3BtoMGA9c
Here's some actual footage of a droplet on a well described more one-off setup:
This American video likely from the 60's shows it with amazing contrast: www.youtube.com/watch?v=_UDT2FcyeA4
Ionizing and non-ionizing radiation by Ciro Santilli 34 Updated 2024-12-15 +Created 1970-01-01
420 to 680 nm for sure, but larger ranges are observable in laboratory conditions.
It would be boring if we could only simulate the same condition all the time, so let's have a look at the different boundary conditions that we can apply to the cell!
We are able to alter things like the composition of the external medium, and the genome of the bacteria, which will make the bacteria behave differently.
The variant selection is a bit cumbersome as we have to use indexes instead of names, but one you know what you are doing, it is fine.
Of course, genetic modification is limited only to experimentally known protein interactions due to the intractability of computational protein folding and computational chemistry in general, solving those would bsai.
NCBI taxonomy entry: www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=511145 This links to:
- genome: www.ncbi.nlm.nih.gov/genome/?term=txid511145 From there there are links to either:
- Download the FASTA: "Download sequences in FASTA format for genome, protein"For the genome, you get a compressed FASTA file with extension
.fna
calledGCF_000005845.2_ASM584v2_genomic.fna
that starts with:>NC_000913.3 Escherichia coli str. K-12 substr. MG1655, complete genome AGCTTTTCATTCTGACTGCAACGGGCAATATGTCTCTGTGTGGATTAAAAAAAGAGTGTCTGATAGCAGCTTCTGAACTG
- Interactively browse the sequence on the browser viewer: "Reference genome: Escherichia coli str. K-12 substr. MG1655" which eventually leads to: www.ncbi.nlm.nih.gov/nuccore/556503834?report=graphIf we zoom into the start, we hover over the very first gene/protein: the famous (just kidding) e. Coli K-12 MG1655 gene thrL, at position 190-255.The second one is the much more interesting e. Coli K-12 MG1655 gene thrA.
- Gene list, with a total of 4,629 as of 2021: www.ncbi.nlm.nih.gov/gene/?term=txid511145
Unlisted articles are being shown, click here to show only listed articles.