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Ciro Santilli @cirosantilli 37

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 Incoming links: David Goodsell

James Somers Updated 2025-07-16
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  • jsomers.net/
  • www.linkedin.com/in/james-somers-4703364/
Huge interest overlap with Ciro Santilli, e.g. he's into
  • molecular biology in general: I should have loved biology by James Somers
  • JCVI-syn3.0: www.newyorker.com/magazine/2022/03/07/a-journey-to-the-center-of-our-cells
  • cryo-EM: www.newyorker.com/magazine/2022/03/07/a-journey-to-the-center-of-our-cells
  • David Goodsell: www.newyorker.com/magazine/2022/03/07/a-journey-to-the-center-of-our-cells
  • History of Google: www.newyorker.com/magazine/2018/12/10/the-friendship-that-made-google-huge
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JCVI-syn3A Updated 2025-07-16
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essential metabolism for a minimal cell (2019) mentions:
JCVI-syn3A, a robust minimal cell with a 543 kbp genome and 493 genes, provides a versatile platform to study the basics of life.
NCBI: www.ncbi.nlm.nih.gov/nuccore/CP016816.2
Based on JCVI-syn3.0, they've added a few genes back to give better phenotypes, including slightly faster duplication time. Because the development cycle time is your God is also true in biology.
As of essential metabolism for a minimal cell (2019) it had only 91 genes of unknown function! So funny.
Bibliograpy:
Figure 1.
JCVI-syn3A during cell division by David Goodsell (2022)
Source. A description is present at: cdn.rcsb.org/pdb101/goodsell/2022_JCVI-syn3A.pdf Integrative Illustration of a JCVI-syn3A Minimal Cell by David Goodsell (2022) which describes everything in the picture.
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Total articles: 3
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