Cathepsin zymography is a laboratory technique used to visualize and analyze the activity of cathepsins, which are a family of cysteine proteases, in biological samples. Cathepsins are involved in various physiological processes, including protein degradation, antigen processing, and apoptosis, and they have been implicated in several diseases, such as cancer and neurodegenerative disorders.
Cell-free protein arrays (CFPAs) are an innovative technology used in protein research that enable the rapid and high-throughput production and screening of proteins. Unlike traditional methods that require living cells for protein synthesis, cell-free systems utilize extracts from cells (often reticulocyte lysates or bacterial extracts) that contain all the necessary components for protein translation.
Cell biology, also known as cytology, is the branch of biology that studies the structure, function, and behavior of cells, which are the fundamental units of life. It encompasses various aspects, including: 1. **Cell Structure**: Understanding the various components of cells, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi apparatus, and cellular membranes.
Cell engineering is a multidisciplinary field that focuses on the design, manipulation, and optimization of cells for various applications, particularly in biotechnology, medicine, and synthetic biology. It encompasses a range of techniques and approaches aimed at modifying cellular functions, behaviors, and characteristics to achieve specific goals. Key areas within cell engineering include: 1. **Genetic Engineering:** Techniques such as CRISPR-Cas9 and recombinant DNA technology are used to modify the genetic material of cells.
Cellosaurus is a comprehensive and curated knowledge database that focuses on cell lines, which are cultures of cells used in biological research. It provides information about various cell lines, including their origin, characteristics, history, and applications in research, as well as any associated publications. This resource is valuable for researchers in fields such as cancer biology, drug discovery, and genetics, as it helps them identify and understand the specific cell lines they may be using in their studies.
Cellular noise refers to the background noise that is present within a cellular system, affecting the quality of communication and data transmission. In the context of mobile telecommunications and cellular networks, noise can originate from various sources, including: 1. **Thermal Noise**: Generated by the random motion of electrons in electronic components, thermal noise is inherent in all electronic devices and can limit the performance of receivers in cellular phones and base stations.
Cell–cell fusogens are proteins or molecules that promote the fusion of two adjacent cells, allowing their membranes to merge and ultimately leading to the formation of a single cell or a multinucleated structure. This process is crucial for various biological functions, including tissue development, immune responses, and viral infections. Fusogens can be found in many organisms, including viruses, where they play a key role in facilitating the entry of viral particles into host cells.
Cell–cell interaction refers to the various ways in which cells communicate, interact, and influence each other's behavior within a tissue or organism. These interactions are crucial for a wide range of biological processes, including development, immune responses, tissue repair, and homeostasis. There are several key mechanisms through which cell–cell interactions occur: 1. **Direct Contact**: Cells can interact through direct physical contact, where proteins on the surface of one cell bind to receptors on another.
The central dogma of molecular biology is a framework that describes the flow of genetic information within a biological system. It outlines the process through which DNA is transcribed into messenger RNA (mRNA), which is then translated into proteins. The central dogma can be summarized in three main steps: 1. **Replication**: The process by which DNA is copied to produce two identical DNA molecules. This is crucial for cell division and the transmission of genetic information to daughter cells.
ChIP-exo, or Chromatin Immunoprecipitation followed by exonuclease treatment, is an advanced technique used to study protein-DNA interactions within the context of chromatin. It is an enhancement of the traditional ChIP (Chromatin Immunoprecipitation) method, which allows researchers to investigate how proteins, such as transcription factors and histones, bind to specific regions of the DNA in vivo.
ChIP-on-chip, or Chromatin Immunoprecipitation on Chip, is a technique used to study the interaction between proteins and DNA in the context of the chromatin. It combines chromatin immunoprecipitation (ChIP) with microarray technology (chip) to analyze how specific proteins, typically transcription factors or histones, bind to particular regions of the genome.
Chargaff's rules are crucial principles in molecular biology that describe the base composition of DNA. Proposed by biochemist Erwin Chargaff in the 1950s, they can be summarized as follows: 1. **Base Pairing Rules**: In any given DNA molecule, the amounts of adenine (A) are equal to the amounts of thymine (T), and the amounts of guanine (G) are equal to the amounts of cytosine (C).
A chemotaxis assay is a laboratory technique used to study the movement of cells in response to chemical signals in their environment. This process, known as chemotaxis, is a crucial mechanism by which cells navigate toward or away from various chemical stimuli, which can include nutrients, pheromones, and toxins.
China National GeneBank (CNGB) is a major biogenetic research facility located in Shenzhen, China. It was established to support the national strategy for biological resources and to promote research in genomics, biotechnology, and biodiversity. The bank serves as a repository of genetic material, including DNA, RNA, and other biological samples, and is aimed at facilitating research in various fields such as agriculture, medicine, and environmental science.
Chlororespiration is a metabolic process observed in certain photosynthetic microorganisms, particularly in some green algae and cyanobacteria. This process involves the use of chlorophyll-containing organelles or chloroplasts to drive respiration in the absence of light. In more traditional terms, respiration generally refers to the process of converting organic compounds into energy through oxidation, typically using oxygen.
Chromatin assembly factor 1 (CAF-1) is a protein complex that plays a crucial role in DNA replication and chromatin assembly. It is primarily involved in the deposition of histones onto newly synthesized DNA during the S phase of the cell cycle. CAF-1 helps to ensure that newly replicated DNA is properly packaged into chromatin, which is essential for maintaining the structure of the genome and regulating gene expression.
A chromatosome is a structural unit of chromatin, which is the material that makes up chromosomes in eukaryotic cells. It consists of a segment of DNA wrapped around a core of histone proteins, specifically containing a core histone octamer made up of two copies each of histone proteins H2A, H2B, H3, and H4, along with an additional molecule of the histone H1.