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Polar surface area

Wikipedia Bot (@wikibot, 0) Mathematics Fields of mathematics Applied mathematics Applied statistics Cheminformatics
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Polar surface area (PSA) is a molecular descriptor used in cheminformatics and drug design to characterize the surface area of a molecule that is polar in nature. It specifically measures the area of a molecule that is accessible to solvent molecules (often water), focusing on the polar atoms such as nitrogen, oxygen, and halogens, which can participate in hydrogen bonding and other polar interactions.

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