Rare-cutter enzyme

Rare-cutter enzymes, also known as rare-cutting restriction enzymes or rare-cutting endonucleases, are a type of restriction enzyme that recognize specific DNA sequences and cut the DNA at sites that are relatively spaced apart from each other. Unlike common restriction enzymes that typically generate blunt or sticky ends by cutting within or near the recognition site, rare-cutters usually leave longer uncut DNA sequences between their cut sites.