A Drosophila Piwi-family protein participating in germline piRNA-mediated regulation, including ping-pong amplification.
It binds selected small RNAs and participates in transcript recognition and cleavage within a germline defence network. Its relationship with AGO3 helps amplify appropriate guide molecular populations, linking molecular specificity to transposon control. [ref]
An epigenetic role for maternally inherited piRNAs in transposon silencing by Julius Brennecke and others. 2008, inherited piRNAs and transposon repression
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