 cGMP-dependent protein kinase

A kinase regulated by cyclic guanosine monophosphate, implicated in several physiological and behavioural processes.

Binding of the cyclic nucleotide changes regulatory interactions and promotes catalytic activity toward selected protein substrates. This couples a second messenger to phosphorylation. A behavioural phenotype involving one family member does not establish an identical role for every cGMP-regulated kinase. ^[ref]