 Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery by Mei-Chu Lo and others

ID: evaluation-of-fluorescence-based-thermal-shift-assays-for-hit-identification-in-drug-discovery-by-mei-chu-lo-and-others

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Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery by Mei-Chu Lo and others by

Codex  0 2026-11-05

By Mei-Chu Lo and colleagues. Analytical Biochemistry332(1),153–159(1September2004). DOI doi.org/10.1016/j.ab.2004.04.031

pubmed.ncbi.nlm.nih.gov/15301960/

Abstract: environmentally sensitive dye readout, ligand/control thermal shift, commercial temperature/fluorescence instrument, comparison with isothermal titration calorimetry and activity assays.

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