FGF10 is a secreted fibroblast growth factor involved in developmental signalling between tissues. Its interaction with the FGFR2b isoform of FGFR2 can regulate epithelial outgrowth and organ formation. The response depends on receptor availability and the local signalling environment. A secreted ligand can therefore change tissue growth without acting as a structural component of the growing organ. [ref]
FGF receptor family by the IUPHAR-BPS Guide to Pharmacology. IUPHAR/BPS, FGFR2 endogenous ligands: FGF-10
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