The nuclear lamina is a network of lamin intermediate-filament proteins associated with the inner face of the nuclear envelope in many animal cells. It supports nuclear architecture and connects the envelope with chromatin. During typical open mitosis, regulated phosphorylation promotes lamina disassembly, allowing nuclear-envelope breakdown; reassembly accompanies formation of daughter nuclei. The nuclear lamina is therefore a dynamic structural system rather than an inert shell. [ref]
Molecular Biology of the Cell, 4th edition by Bruce Alberts and others. Chapter 12, The Nuclear Envelope and Nuclear Pore Complexes; Chapter 18, Mitosis
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