Solution

ID: past-exam-of-the-further-mathematical-biology-course-of-the-university-of-oxford/2023/2/a/i/solution

Put . The nullclines of the space-clamped FitzHugh-Nagumo model are
The first nullcline is a downward-leading cubic polynomial, shifted vertically by ; the second nullcline is a line through the origin with slope . Their intersections satisfy
Writing , differentiation gives
If , increases strictly, so there is exactly one equilibrium. If , is still strictly increasing, although its derivative vanishes at one point, so the equilibrium is again unique. If , define
Here has a local maximum at and a local minimum at ; therefore
At either endpoint there are two distinct equilibria, one a double root. These are the saddle-node bifurcation boundaries omitted by the generic one-or-three wording. At and there is one triple root. This is the Cubic FitzHugh-Nagumo nullcline criterion.
Figure 1.
One and three intersections of the FitzHugh-Nagumo model nullclines
. Details.

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