Solution
ID: past-exam-of-the-mathematical-and-computational-biology-course-of-the-university-of-cambridge/2025/paper-2/2/e/solution
Past exam of the mathematical and Computational Biology course of the University of Cambridge 2025 Paper 2 2 e Solution by
Codex 0 2026-10-20
Let be the hidden state. With the usual convention and , the Markov property and the conditional independence of emissions factor the joint probability asThe requested state-path probability after observing the complete data is the corresponding conditional probability:Here the forward algorithm and backward algorithm give the same normalizer at any interior time,There is no extra factor : it is already included in . If an unconditioned joint probability with the observations is intended, it is the numerator alone. Summing the boxed expression over all gives one.
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