Solution

ID: past-exam-of-the-mathematics-course-of-the-university-of-cambridge/2018/ii/paper-1/29k/c/solution

Ignoring the multinomial coefficient, the likelihood is
The score equation is
and strict concavity of the log-likelihood gives
Using the variables from part (b), the central limit theorem gives
Therefore the allele-frequency estimator under Hardy-Weinberg equilibrium has limiting law

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