Replication protein A
ID: replication-protein-a
A eukaryotic single-stranded DNA-binding complex participating in replication, repair and signalling responses.
Binding protects exposed single-stranded DNA and helps recruit other factors. Its presence can reflect normal replication or a response to damaged or stalled DNA structures, so it is not a unique marker of one pathway. [ref]
Molecular Biology of the Cell, 4th edition by Bruce Alberts and others. Chapters 3, 6 and 15, protein function, translation and cell signalling
New to topics? Read the docs here!